What is Osteoarthritis (OA)? Osteoarthritis is a Non Inflammatory disease that affects many joints, knee joint most common and its importance derives from its economic impact, in terms of both productivity (single greatest cause of days lost from work) and cost of treatment (chronic use of analgesics and anti-inflammatory drugs). In normal joint, a firm, rubbery material called cartilage covers the end of each bone. Cartilage provides a smooth, gliding surface for joint motion and acts as a cushion between the bones. In Osteoarthritis, the cartilage breaks down, causing pain, swelling and problems moving the joint. This disease, that mostly affects women, worsens over the time and should be treated as early as possible.